At SBRI, we drive scientific innovation and harness emerging technologies to advance global health through key research discoveries. Technology has become increasingly important to scientific research, moving discoveries along at a rate never thought possible just a few short years ago. Our scientists often say that today’s technologies allow them to accomplish in one week what previously took years.

Peter Myler, Ph.D., heads SBRI’s bioinformatics efforts, centered around the use of computers to extract and analyze biological data, particularly in studying the nucleotide sequences of DNA and other nucleic acids. Dr. Myler’s most recent work resulted in the completion of a draft sequence of the genome of Leishmania major friedlin, the parasite responsible for cutaneous leishmaniasis.

Our scientists are increasingly using high-throughput genome-wide approaches to answer biological questions. Examples of approaches currently being developed at SBRI include genome sequencing, DNA microarray analysis of expression, proteomics and structural genomics. The immense amount of data revealed by these technologies is key to the discovery of accurate diagnostics, safe and effective vaccines, and promising drugs for infectious diseases.

Some of our advanced technologies include:

DNA Sequencing: Reveals the sequence of an organism's DNA and facilitated gene discovery, as well as comparisons between hosts and pathogens.  SBRI provides DNA sequencing services and analysis to the Institute in addition to outside academic and non-academic users.  Click here for the SBRI Sequencing Facility.

DNA Microarrays: Shows patterns of gene activity under different conditions.

Mass Spectroscopy: Analyzes protein sequence and provides clues to structure and function.

Some of these technologies are available for use by academic or other not-for-profit organizations.  Click here for shared technical services. 

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