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Leonidas Stamatatos, Ph.D.

		Full Member, Seattle Biomedical Research Institute Viral Vaccines Program Director Affiliate Professor Department of Global Health  University of Washington Email: leo.stamatatos@sbri.org Disease under study: HIV

Mission
The emphasis of Dr. Stamatatos’ work is to develop a safe and effective vaccine to combat the spread of  HIV and to investigate how HIV infection leads to AIDS.

Research
A major area of interest for our team is to better understand how neutralizing antibodies against HIV are developed during natural HIV-infection. We are particularly interested in: a) identifying factors influencing the development of such antibodies by HIV+ subjects, b) understanding how the virus evolves to avoid the action of such antibodies, and c) identifying the particular HIV epitopes that these antibodies target

Another major research focus is the comparative evaluation of various approaches to design novel HIV vaccines to elicit neutralizing antibodies against all viral variants circulating in the world.  

Themes
     *  HIV envelope structure/function relationship
     *  HIV transmission and pathogenesis
     *  HIV vaccine design

Primary Collaborations
     *  University of Washington
     *  Fred Hutchinson Cancer Research Center
     *  California Institute of Technology
     *  Washington National Primate Research Center
     *  Novartis, Vaccines and Diagnostics
     *  Southwest Foundation for Biomedical Research

Dr. Stamatatos’ research is currently supported by the National Institutes of Health (NIH)
and the Bill & Melinda Gates Foundation.

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