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Donald Sodora, Ph.D.

Selected Publications

Silvestri, G., M. Paiardini, I. Pandrea, M.M. Lederman and D.L. Sodora. 2007. Understanding the benign nature of SIV infection in natural hosts (Review). Journal of Clinical Investigation. In Press.

D.L. Sodora and G. Silvestri. Immune activation and AIDS pathogenesis (Review). AIDS. In Press. 

Okoye, A., M. Meier-Schellersheim, J.M. Brenchley, S.I. Hagen, J.M. Walker, M. Rohankhedkar, Richard Lum, John B. Edgar, Shannon L. Planer, A. Legasse, A.W. Sylwester, M. Piatak, Jr., J.D. Lifson, V.C. Maino, D.L. Sodora, D.C. Douek, M.K. Axthelm, Z.Grossman, and L.J. Picker. 2007. Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. Journal of Experimental Medicine. 204(9):2171-2185. PMID: 17724130

Milush, J.M., J.D. Reeves, S. Gordon, D. Zhou, A. Muthukumar, D. Kosub, E. Chacko, L. Giavedoni, C.C. Ibegbu, K. Stefano-Cole, J. Miamidian, M. Paiardini, A.P. Barry, S. Staprans, G. Silvestri and D.L. Sodora. 2007. Virally-induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host. Journal of Immunology, 179(5):3047-3056. PMID: 17709519

Gordon, S.N., S.E. Bosinger, J.M. Brenchley, N.R. Klatt, J.M. Milush, J.C. Engram, R.M. Dunham, M. Paiardini, E.A. Strobert, C. Apetrei, I.V. Pandrea, D.C. Douek, D. Kelvin, S.I. Staprans, D.L. Sodora, and G. Silvestri. 2007. Severe depletion of mucosal CD4+ T-cells in AIDS-free SIV-infected sooty mangabeys. Journal of Immunology, In Press. PMID: 17709517

Milush, J.M., K. Stefano-Cole, K. Schmidt, A. Durudas, I. Pandrea, and D.L. Sodora. 2007. Mucosal innate immune response associated with a timely adaptive immune response and slower disease progression following oral transmission of SIV in rhesus macaques. Journal of Virology, 81(12):6175-6186. PMID: 17428863

Apetrei, C., R. Gautam, B. Sumpter, A.C. Carter, T. Gaufin, S.I. Staprans, J. Else, M. Barnes, R. Cao, S. Garg, J.M. Milush, D.L. Sodora, I. Pandrea, and G. Silvestri. 2007. Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys. Journal of Virology. 81(15)7913-7923.  PMID: 17507488

B. Sumpter, R. Dunham, S. Gordon, J. Engram, M. Hennessy, A. Kinter, M. Paiardini, B. Cervasi, N. Klatt, H. McClure, J.M. Milush, S. Staprans, Donald L. Sodora, and G. Silvestri. 2007. Correlates of preserved CD4+ T-cell homeostasis during natural, non-pathogenic SIV infection of sooty mangabeys: implications for AIDS pathogenesis. Journal of Immunology, 178(3):1680-1691. PMID: 17237418

Schindler M., J. Munch, O. Kutsch, H. Li, M.L. Santiago, F. Bibollet-Ruche, M.C. Muller-Trutwin, F.J. Novembre, M. Peeters, V. Courgnaud, E. Bailes, P. Roques, D.L. Sodora, G. Silvestri, P.M. Sharp, B.H. Hahn and F. Kirchoff. 2006. Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell. 16;125(6):1055-67. PMID: 16777597

Muthukumar, A., D. Zhou, M. Paiardini, A.P. Barry, K.S. Cole, H.M. McClure, S.I. Staprans, G. Silvestri, and D.L. Sodora. 2005. Timely triggering of homeostatic mechanisms involved in the regulation of T cell levels in SIVsm infected sooty mangabeys. Blood, Dec 1; 106(12):3839-45. PMID: 16105985

Milush, J.M., D. Kosub, M. Marthas, K. Schmidt, F. Scott, A. Wozniakowski, C. Brown, S. Westmoreland, and D.L. Sodora. 2004. HIV Transmission Model Reveals Rapid Dissemination of SIV Following Oral Inoculation. AIDS, 18:2371-2380.  PMID: 15622313

Muthukumar A., A. Wozniakowski, M-C, Gauduin, M. Paiardini, H.M. McClure, R. P. Johnson, G. Silvestri, and D.L. Sodora. 2004. Elevated Interleukin-7 Levels are not Sufficient to Maintain T-cell Homeostasis During Simian Immunodeficiency Virus Induced Disease Progression. Blood, Feb 1; 103(3): 973-9. PMID: 14525780

Silvestri, G., D.L. Sodora, R.A. Koup, S.P. O'Neil, W.J. Kaiser, H.M. McClure, S.I. Staprans and M.B. Feinberg. 2003. Non-Pathogenic simian immunodeficiency virus infection of sooty mangabey monkeys is characterized by limited bystander immunopathology and preserved immune regenerative capacity despite chronic high level virus replication. Immunity, 18(3):441-452. PMID: 12648460

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