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David Sherman, Ph.D.

Selected Publications

Wisedchaisri G, Wu M, Rice AE, Roberts DM**, Sherman DR and Hol WGJ.  Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency.  J Mol Biol, 2005, 354:630-41. PMID: 1624638

Fortune SM, Jaeger A, Chase MR, Sarracino DA, Sassetti CM, Sherman DR, Bloom BR and Rubin EJ.  Mutually-dependent secretion of proteins required for mycobacterial virulence.  Proc. Natl. Acad. Sci, USA 2005, 102:10676-81. PMID: 16030141

Volkman HE, Clay H, Beery D, Chang JCW*, Sherman DR, Ramakrishnan L.   Tuberculous granuloma formation is enhanced by a Mycobacterium virulence determinant.  Public Library of Science Biology, 2004, 2:1946-56. PMID: 15510227

Roberts DM**, Liao RP, Wisedenchari G, Hol W, Sherman DR.  Two sensor kinases contribute to the hypoxic response of Mycobacterium tuberculosis.  J Biol Chem, 2004, 279:23082-7.  PMID: 15033981

Mehta R, Pearson JT, Mahajan S, Nath A, Hickey MJ, Sherman DR, Atkins WM: Adenylylation and catalytic properties of M. tuberculosis glutamine synthetase expressed in E. coli vs. Mycobacteria. J Biol Chem, 2004, 279:22477-82.  PMID: 15037612

Sherman DR, Guinn KM*, Hickey MJ, Mathur SK**, Zakel, KL, Smith S:  Mycobacterium tuberculosis H36Rv:ΔD1 is more virulent than M. bovis BCG in long-term murine infection.  J Inf Dis, 2004, 190: 123-26.  PMID: 15195251  

Belley A, Di Pietrantonio T, Girard M, Alexander D, Jones J, Schurr E, Liu  J, Sherman DR, Behr  MA.  Impact of methoxymycolic acid production by M. bovis BCG vaccines.  Infect Immun, 2004, 72: 2803-09.  PMID: 15102790

Mostowy S, Cleto C, Sherman DR, Behr M: The Mycobatcerium tuberculosis complex trasncriptome of attenuation.  Tuberculosis, 2004;84: 197-204.   PMID: 15207489

Guinn KM*, Hickey MJ, Mathur SK**, Zakel KL, Grotzke JE, Lewinsohn DM, Smith S, Sherman DR: Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.  Mol Microbiol, 2004, 51(2):359-370.  PMID: 14756778

Voskuil MI, Schnappinger D, Harrell  MI*, Visconti KC, Dolganov G, Sherman DR, Schoolnik GK: Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program.  J Exp Med, 2003, 198(5):705-13.   PMID: 12953092

Park HD, Guinn KM*, Harrell MI*, Liao R, Voskuil MI, Tompa M, Schoolnik GK, Sherman DR: Rv3133c/dosR is a transcription factor that mediates the hypoxic response of M. tuberculosis.  Mol Microbiol, 2003, 48(3):833-843.  PMID: 12694625

Lewis KN**, Liao R, Guinn KM*, Smith S, Hickey MJ, Behr MA, Sherman DR: Deletion of RD1 from M. tuberculosis mimics BCG attenuation.  J Inf Dis, 2003, 187: 117-123.  PMID: 12508154

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