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Stefan H. I. Kappe, Ph.D.

Selected Publications
Mueller AK, Camargo N, Kaiser K, Andorfer C, Frevert U, Matuschewski K, Kappe SH. Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci 2005 Feb 22;102(8):3022-7. PMID: 15699336

Mueller, AK, Labaied M, S.H.I. Kappe* and K Matuschewski* (2005). Genetically modified Plasmodium parasites as protective live attenuated experimental malaria vaccine.  Nature. 443, 164-167 *Equal contribution.  PMID: 15580261

Kaiser, K., Matuschewski, K., Camargo, N., Ross, J. and S. H. I. Kappe (2004) Differential transcriptome profiling identifies Plasmodium genes encoding pre-erythrocytic stage-specific transcripts. Molecular Microbiology. 51, 1221-1232.  PMID: 14982620

Kappe, S. H. I., Buscaglia, C. A., Bergman, L. W., Coppens, I. and Victor Nussenzweig (2004) Apicomplexan gliding motility and host cell invasion: overhauling the motor model. Trends in Parasitology. 20, 13-16.  PMID: 14700584

Kappe, S. H. I., Buscaglia, C. A. and V. Nussenzweig. (2004) Plasmodium sporozoite molecular cell biology. Annu. Rev. Cell Dev. Biol. 20, 29-59. PMID:  15473834

Kaiser, K., Camargo, N., Coppens, I., Vaidya, A., Morrisey, J. M. and S. H. I. Kappe A member of a conserved Plasmodium protein family with membrane attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites. Molecular and Biochemical Parasitology, 133, 15-36. PMID: 14668008. 

Kaiser, K., Camargo, N. and S. H. I. Kappe (2003) Transformation of sporozoites into early exoerythrocyticmalaria parasites does not require host cells. Journal of Experimental Medicine. 197, 1045-1050. PMID: 12707302

Kappe, S. H. I., Kaiser, K., and K. Matuschewski (2003) The Plasmodium sporozoite journey: a rite of passage. Trends in Parasitology. 19, 135-143. PMID: 12643997

Bergman, L. W., Kaiser, K., Fujioka, H., Coppens, I., Daly, T. M., Fox, S., Matuschewski, K.,Nussenzweig, V., and S. H. I. Kappe (2003) Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. Journal of Cell Science 116, 39-49. PMID: 12456714

Matuschewski, K., Ross, J., Brown, S. M, Kaiser K., Nussenzweig, V. and S. H. I. Kappe (2002) Infectivity-associated changes in the transcriptional repertoire of the malaria parasite sporozoite stage. Journal of Biological Chemistry, 277, 41948-41953. PMID: 12177071

Blair, P. L., Kappe, S. H. I., Maciel, J. E., Balu, B. and J. H Adams (2002) Plasmodium falciparum MAEBL is a unique member of the ebl family. Molecular and Biochemical Parasitology 122, 35-44. PMID: 12076768

Kappe, S. H. I., Gardner, M. J., Brown, S. M, Ross, J., Matuschewski, K., Ribeiro, J. M., Adams, J. H., Quackenbush, J., Cho, J., Carucci, D. J., Hoffman, S. L. and V. Nussenzweig (2001) Exploring the transcriptome of the malaria sporozoite stage. Proceedings of the National Academy of Sciences USA 98, 9895-9900. PMID:11493695

Fraser, T. S., Kappe, S. H. I., Narum, D. L., Buskirk, K. M. and J. H. Adams (2001) Erythrocyte-binding activity of Plasmodium yoelii apical membrane antigen-1 expressed on the surface of transfected COS-7 cells . Molecular and Biochemical Parasitology 117, 49-59. PMID: 11551631

Matuschewski, K., Mota, M. M., Pinder, J. C., Nussenzweig, V. and S. H. I Kappe (2001) Identification of the class XIV Myosins Pb-MyoA and Py-MyoA and expression in Plasmodium sporozoites. Molecular and Biochemical Parasitology 112, 157-161. PMID: 11166399

Kappe, S. H. I., Bruderer, T., Gantt, S., Fujioka, H., Nussenzweig, V. and Robert Menard (1999) Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites.  The Journal of Cell Biology, 147, 937-943.  PMID: 10579715.

Kappe, S. H. I., Noe, A. R., Fraser T. S., Blair, P. L. and J. H. Adams (1998) A family of chimeric erythrocyte binding proteins of malaria parasites. Proceedings of the National Academy of Sciences USA 95, 1230-1235. PMID: 9448314

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