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Joseph D. Smith, Ph.D.

Selected Publications
Bockhorst J., Lu, F., Janes J.H., Keebler J., Gamain B., Awadalla P., Su X., Jojic N., and J.D. Smith. (2007) Structural polymorphism and diversity selection on the pregnancy malaria vaccine candidate VAR2CSA. Mol. Biochem. Parasitol. in press. PMID: 17669514

Kraemer S.M, Kyes S.A., Aggarwal G., Springer A.L., Nelson S.O., Christodoulou Z., Smith L.M., Wang W., Levin E., Newbold C.L., Myler P.J., and J.D. Smith. (2007) Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparison of geographically diverse isolates. BMC Genomics. 8:45-63. PMID: 17286864

Trimnell A., Kraemer S.M., Mukherjee S., Phippard D.J., Janes J.H., Flamoe E., Su, X., Awadalla P., and J.D. Smith. (2006) Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria. Mol. Biochem. Parasitol. 148(21:169-80). PMID: 16697476

Gamain B., Trimnell, A.R., Scheidig C., Scherf A., Miller L.H., and J.D. Smith. (2005) Identification of multiple CSA binding domains in the var2csa gene transcribed in CSA binding parasites. J. Infect. Dis. 191:1010-3. PMID: 15717280

Springer A.L., Smith, L.M., Mackay D.Q., Nelson S.O., and J.D. Smith. (2004) Functional Interdependence of the DBLbeta domain and c2 region for binding of the Plasmodium falciparum variant antigen to ICAM-1. Mol. Biochem. Parasitol. 137:55-64. PMID: 15279951

Kraemer, S.M. and J.D. Smith. (2003) Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family. Molecular Microbiology. 50:1527-38. PMID: 14651636

Robinson B, Welch TL, and Smith JD. Widespread functional specialization of Plasmodium falciparum erythrocyte membrane protein 1 family members to bind CD36 analyzed across a parasite genome. 2003. Molecular Microbiology. 47:1265-78. PMID: 12603733

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