Objectives
Principal Investigators
 . Gerard Cangelosi
 . Patrick Duffy
 . Jean Feagin
 . Michal Fried
 . Malcolm Gardner
 . Nancy Haigwood
 . Helen Horton
 . Stefan Kappe
 . Peter Myler
 . Marilyn Parsons
 . David Sherman
 . Arnold Smith
 . Joseph Smith
 . Don Sodora
 . Leonidas Stamatatos
 . Ken Stuart
 . Ruobing Wang
 . Theodore White
Senior Scientists
Staff Scientists
Collaborations
Core Technologies

   
 

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Malcolm Gardner, Ph.D.

Education

Ph.D. Biochemistry Sept. 1980-Nov. 1985 University of Tennessee - Oak Ridge Graduate School of Biomedical Sciences, Biology Division, Oak Ridge National Laboratory, Oak Ridge, TN
B.S. Honors in Biology  1980 Dickinson College, Carlisle, PA

 

Professional Experience
2005 – Present Full Member, Seattle Biomedical Research Institute
2003-2005 Investigator, Parasite Genomics Group, The Institute for Genomic Research, Rockville, MD
1999-2003 Associate Investigator, Parasite Genomics Group, The Institute for Genomics Research, Rockville, MD
1997-1999 Assistant Investigator, Department of Eukaryotic Genomics, The Institute for Genomic Research, Rockville, MD
1995 - 1997 Research Assistant Professor, Department of Microbiology and Immunology, University of Maryland at Baltimore, Baltimore, MD
1993-1997 Senior Molecular Biologist, Malaria Program, Naval Medical Research Institute, Rockville, MD
1991-1993 National Research Council Senior Fellow, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Washington, DC
1985-1991 Postdoctoral Fellow, Division of Parasitology, National Institute for Medical Research, London, England

Select Honors and Awards
     1997-1996     Letters of Commendation (2), Naval Medical Research Institute
     1991             National Research Council Senior Fellow
     1981             National Research Service Award    

Field of Study
I entered the malaria field as a postdoc at the National Institute for Medical Research in London, drawn by the realization that malaria was a tremendously important but relatively under-studied disease.  I thought that there was a great deal yet to be learned about the parasite at the molecular level.  I subsequently had a "once-in-a-lifetime" opportunity to participate in the Plasmodium falciparum genome project while working at The Institute for Genome Research.  The genome sequence that was determined with our partners at the Wellcome Trust Sanger Institute, Stanford University, and the Naval Medical Research Center is being used by scientist worldwide to accelerate malaria research and to identify new drug and vaccine targets.

At SBRI, I will extend my previous work in genomics via laboratory investigations to learn more about the biological roles of the apicoplast, an essential parasite organelle that contains novel drug targets but whose functions in the malaria parasite have not been fully characterized.  I will also continue to work on the improvement of the P. falciparum genome annotation, and to collaborate with others at SBRI and elsewhere to identify novel vaccine antigens and drug targets.  I also welcome the opportunity to mentor the next generation of malaria researchers.   
 

 

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