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Nancy Freitag, Ph.D.

Selected Publications
 

Mueller, K. J. and Freitag, N. E. Pleiotropic enhancement of bacterial pathogenesis resulting from the constitutive activation of the Listeria monocytogenes regulatory factor PrfA. Infect. Immun., 73: 1917 – 1926, 2005. PMID: 15784531 

Wong, K. Y. K.** and Freitag, N. E. A novel mutation within the central Listeria monocytogenes regulator PrfA that results in constitutive expression of virulence gene products. J. Bacteriol., 186: 6265 – 6276, 2004. PMID: 15342597

Lukowiak, A. M, Mueller, K. J., Freitag, N. E., and Youngman, P. Deregulation of Listeria monocytogenes virulence gene expression by two distinct and semi-independent pathways. Microbiol. 150: 321 – 333, 2004. PMID: 14766910

Way, S., Thompson, L. J., Lopes, J. E., Hajjar, A. M., Kollman, T. R., Freitag, N. E., and Wilson, C. B. Characterization of flagellin expression and its role in Listeria monocytogenes infection and immunity. Cell. Microbiol. 6: 235-242, 2004. PMID: 14764107

Wong, K. Y. K.**, Bouwer, H. G. A., and Freitag, N. E. Evidence implicating the 5' untranslated region of Listeria monocytogenes actA in the regulation of bacterial actin-based motility. Cell. Microbiol. 6: 155 – 166, 2004. PMID: 14706101

Mansfield, B. E.,* Dionne, M. S., Schneider, D. S., and Freitag, N. E. Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cell. Microbiol., 5:901 – 911, 2003.  PMID: 14641175

Shetron-Rama, L. M., Mueller, K., Bravo, J. M., Bouwer, H. G. A., and Freitag, N. E. Isolation of Listeria monocytogenes mutants with high level in vitro expression of host cytosol-induced gene products. Mol. Microbiol., 48: 1537 - 1551, 2003. PMID: 12791137

Greene, S. L. and Freitag, N. E. Negative regulation of PrfA, the key activator of Listeria monocytogenes virulence gene expression, is dispensable for bacterial pathogenesis. Microbiol. 149: 111 - 120, 2003. PMID: 12576585

Shetron-Rama, L. M., H. Marquis, H. G. Bouwer, and Freitag, N. E. Intracellular induction of Listeria monocytogenes actA expression. Infect. Immun. 70: 1087 – 1096, 2002. PMID: 11854187

Drevets, D. A., Jelinek, T. A., and Freitag, N. E. Listeria monocytogenes-infected phagocytes can initiate central nervous system infection in mice. Infect. Immun. 69: 1344-1350, 2001. PMID: 11179297

Williams, J. R., Thayyullathil, C, and Freitag, N. E. Sequence variations within PrfA DNA binding sites and effects on Listeria monocytogenes virulence gene expression. J. Bacteriol, 182: 837 – 841, 2000. PMID: 10633124

Teitelbaum, R., Cammer, M., Maitland, M. L., Freitag, N. E., Condeelis, J, and Bloom, B. R. Mycobacterial infection of macrophages results in membrane-permeable phagosomes. Proc. Natl. Acad. Sci. USA 96: 15190-15195, 1999. PMID: 10611360

Freitag, N. E. and Jacobs, K. E. Examination of Listeria monocytogenes intracellular gene expression using the green fluorescent protein of Aequoria victoria. Infect. Immun. 67:1844 - 1852, 1999. PMID: 10085026

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