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Jean E. Feagin, Ph.D.

Selected Publications
Harrell, M.I., Coe, K.J., Sands, B., Tami, G., Schnare, M.N., Lee, J., Cannone, J., Gutell, R.R., and Feagin, J.E.  The fragmented mitochondrial rRNAs of Plasmodium falciparum.  (In preparation, expected submission Aug 2007).

Zhang, X., Gallagher, R., and Feagin, J.E.  Coordinated expression of apicoplast genes in Plasmodium falciparum.  (In preparation, expected submission Sept 2007).

Karnataki, A., DeRocher, A., Coppens, I., Feagin, J.E., and Parsons, M.  (2007) A membrane protease is targeted to the relict plastid of Toxoplasma via an internal signal sequence.  Traffic (in press).

Parsons, M., Karnataki, A., Feagin, J.E., and DeRocher, A., (2007)  Protein trafficking to the apicoplast: deciphering the apicomplexan solution to secondary endosymbiosis.  Euk. Cell 6: 1081-1088.PMID: 17513565 

Karnataki, A., DeRocher, A., Coppens, I., Nash, C., Feagin, J.E., and Parsons, M.  (2007) Cell cycle-regulated vesicular trafficking of Toxoplasma APT1, a protein localized to multiple apicoplast membranes.  Mol. Microbiol. 63:1653-1658. PMID: 17367386

Feagin, J.E. and Parsons, M.  (2007) The apicoplast and mitochondrion.  In: Toxoplasma gondii: The Model Apicomplexan—Perspectives and Methods, L. Weiss and K. Kim, eds. London: Academic Press),  pp. 207-244.

Cook, T., Roos, D., Morada, M., Zhu, G., Keithly, J.S., Feagin, J.E., and Yarlett, N.  (2007) Divergent polyamine metabolism in the Apicomplexa.  Microbiol. 153:1123-1130. PMID: 17379721

Rausch, R.L., Feagin, J.E., and Rausch, V.R.  (2007) Sorex rohweri sp. nov. (Mammalia, Soricidae) from northwestern North America. Mamm. Biol. 72:93-105.

DeRocher, A., Gilbert, B., Feagin, J.E., and Parsons, M. (2005). Dissection of brefeldin A sensitive and insensitive steps in apicoplast protein targeting. J. Cell Sci., 118: 565-574. PMID: 15657083

Maréchal, E., Azzouz, N., Santos de Macedo, C., Block, M.A., Feagin, J.E., Schwarz, R.T., and Joyard, J. (2002) Apicomplexan parasites synthesize galactolipids similar to those of chloroplast envelope membranes. Euk. Cell 1:653-656. PMID: 12456013

Ohkanda J, Lockman JW, Yokoyama K, Gelb MH, Croft SL, Kendrick H, Harrell MI, Feagin JE, Blaskovich MA, Sebti SM, Hamilton AD Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. Bioorg. Med. Chem. Lett. 11:761-764. 2001. PMID: 11277514

Li J, Maga JA, Cermakian N, Cedergren R, Feagin JE Identification and characterization of a Plasmodium falciparum RNA polymerase gene with homology to mitochondrial RNA polymerases. Mol. Biochem. Parasitol. 113:261-269. 2001. PMID: 11295180

DeRocher A, Hagen CB, Froelich J, Feagin JE, Parsons M Analysis of targeting sequences demonstrates that trafficking to the Toxoplasma gondii plastid branches off the secretory system. J. Cell Sci. 113:3969-3977. 2000.  PMID: 11058084

Feagin JE Mitochondrial genome diversity in parasites. Int. J. Parasitol. 30:371-390. 2000;  PMID:  10731561

Rehkopf DH, Gillespie DE, Harrell MI, Feagin JE Transcriptional mapping and RNA processing of the Plasmodium falciparum mitochondrial mRNAs. Mol. Biochem. Parasitol. 105:93-103. 2000;  PMID:  10613702 

Gillespie DE, Salazar NA, Rehkopf DH, Feagin JE The fragmented mitochondrial ribosomal RNAs of Plasmodium falciparum have short A tails. Nucleic Acids Res. 27:2416-2422. 1999;  PMID:   10325433

Feagin JE, Mericle BL, Werner E, Morris M Identification of additional rRNA fragments encoded by the Plasmodium falciparum 6 kb element. Nucleic Acids Res. 25:438-446. 1997;  PMID:   9016576 

Ji Y, Mericle BL, Rehkopf DH, Anderson JD, Feagin JE The Plasmodium falciparum 6 kb element is polycistronically transcribed. Mol. Biochem. Parasitol. 81:211-223. 1996;  PMID:  8898336

Feagin JE, Drew ME. Plasmodium falciparum: Alterations in organelle transcript abundance during the erythrocytic cycle. Exp. Parasitol. 80:430-440. 1995;  PMID:  7729478

Feagin JE, Werner E, Gardner MJ, Williamson DH Wilson RJM Homologies between the contiguous and fragmented rRNAs of the two Plasmodium falciparum extrachromosomal DNAs are limited to core sequences. Nucleic Acids Res. 20:879-887. 1992;  PMID:  1542578 

Feagin JE The 6-kb element of Plasmodium falciparum encodes mitochondrial cytochrome genes. Mol. Biochem. Parasitol. 52:145-148. 1992;  PMID: 1320735 

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