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Patrick Duffy, M.D.

Selected Publications
Muehlenbachs A, TK Mutabingwa, M Fried, PE Duffy. 2007. Genome wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection. J Immunol, in press. PMID: 17579077

Oleinikov AV, E Rossnagle, S Francis, TK Mutabingwa, M Fried, PE Duffy. 2007. Effects of sex, parity and antigenic variation on seroreactivity to candidate pregnancy malaria vaccines. J Infect Dis, in Press. PMID: 17538896

M Fried, KK Hixson, L Anderson, TK Mutabingwa, PE Duffy. 2007. The distinct surface proteome of placental malaria parasites. Mol Biochem Parasitol, in press. PMID: 17618698

Dickert N, DeRiemer KL, Duffy PE, Garcia-Garcia L, Mutabingwa TK, Sina B, Tindana P, and Lie R. 2007. Ancillary Care Responsibilities in Observational Research: Two Cases, Two Problems. Lancet, 369 (9564):874-7. PMID: 17350458

Francis SE, Malkov VA, Oleinikov AV, Rossnagle E, Wendler JP, Mutabingwa TK, Fried M, PE Duffy. 2007. Six genes are preferentially expressed by the circulating and sequestered forms of Plasmodium falciparum parasites that infect pregnant women. Infect Immun, in press.

A Muehlenbachs, TK Mutabingwa, M Fried, PE Duffy. 2007. An unusual presentation of placental malaria: a single persisting nidus of sequestered parasites. Human Pathol, 38(3):520-3. Epub 2007 Jan 19. PMID: 17239927

Ntoumi F, Kwiatkowski DP, Diakite M, Mutabingwa TK, PE Duffy. 2007. New interventions for malaria: mining the human and parasite genomes. Am J Trop Med Hyg, in press.

A Muehlenbachs, TK Mutabingwa, S Edmonds, M Fried, PE Duffy. 2006. Hypertension and Maternal-Fetal Conflict during Placental Malaria. PLoS Med, 3:e446. PMID: 17105340

Mutabingwa TK, Bolla MC, Li JL, Domingo GJ, Li X, Fried M, Duffy PE. (2005) Maternal Malaria and Gravidity Interact to Modify Infant Susceptibility to Malaria. PLoS Med. 2005 Nov 8;2(12):e407 [Epub ahead of print] PMID: 16259531

Duffy PE, Mutabingwa TK (2005).  Rolling Back a Malaria Epidemic in South Africa. PLoS Med. 2005 Nov 1;2(11):e368 [Epub ahead of print] PMID: 16187736

Nixon CP, Friedman J, Treanor K, Knopf PM, Duffy PE, Kurtis JD (2005) Antibodies to rhoptry-associated membrane antigen predict resistance to Plasmodium falciparum. J Infect Dis. 2005 Sep 1;192(5):861-9. Epub 2005 Jul 29. PMID: 16088836

Nixon CP, Friedman J, Knopf PM, Duffy PE, Kurtis JD (2005) Protective human immunity as a vaccine discovery tool for falciparum malaria. Transfusion. 2005 Aug;45(2 Suppl):81S-87S. PMID: 16086793

Duffy PE, Krzych U, Francis S, Fried M. (2005) Malaria vaccines: using models of immunity and functional genomics tools to accelerate the development of vaccines against Plasmodium falciparum.
Vaccine. 2005 Mar 18;23(17-18):2235-42. PMID: 15755603

Fried M, Duffy PE (2004) Mass spectrometric analysis of Plasmodium falciparum erythrocyte membrane protein-1 variants expressed by placental malaria parasites. Proteomics Apr;4(4):1086-93. PMID: 15048989

Duffy PE, TK Mutabingwa. 2003. Drug combinations for malaria: Time to ACT? Lancet, 363(9402):3-4. PMID: 14573685

Duffy PE, Fried M. (2003) Antibodies that inhibit P. falciparum adhesion to chondroitin sulfate A are associated with increased birth weight and gestational age of newborns. Infect Immun. 71:6620-3; PMID: 14573685. 

Friedman JF, Kurtis JD, Mtalib R, Opollo M, Lanar DE, Duffy PE. (2003) Malaria related to decreased nutritional status among adolescents and adults in the setting of intense perennial transmission. J Infect Dis. J Infect Dis. 2003 Aug 1;188(3):449-57. Epub 2003 Jul 15;  PMID:  12870128

Gourley IS, Kurtis JD, Kamoun M, Amon JJ, Duffy PE. (2002) Profound bias in interferon-gamma and interleukin-6 allele frequencies in western Kenya, where severe malarial anemia is common in children. J Infect Dis. 186:1007-12.  PMID:  12232842

Kurtis JD, Lanar DE, Opollo MO, Duffy PE Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum. Infect Immun 67:3424-3429. 1999; PMID: 10377122

Fried M, Nosten F, Brockman A, Brabin BJ, Duffy PE Maternal antibodies block malaria. Nature 395:851-852. 1998 PMID: 9804416 

Fried M, Muga RO, Misore AO, Duffy PE Malaria elicits type 1 cytokines in the human placenta: IFN-gamma and TNF-alpha associated with pregnancy outcomes. J Immunol 160:2523-2530. 1998; PMID: 9498798 

Duffy PE, Kaslow DC A novel malaria protein, Pfs28, and Pfs25 are genetically linked and synergistic as falciparum malaria transmission-blocking vaccines. Infect Immun 65:1109-1113. 1997; PMID: 9038325

Fried M, Duffy PE Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 272: 1502-4. 1996; PMID: 8633247

Additional Publications via PubMed (opens in new window)

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